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Novel conjugates of b-lactam antibiotic and host defence peptide to treat infections caused by multidrug-resistant bacteria

Introduction b-Lactam antibiotics have been in clinical use for more than 65 years and have proven to be safe and efficient. They include penicillins, cephalosporins, monobactams and carbapenems. The market for b-lactam antibiotics has been valued at US$ billion 8.1 in 2002, representing 52% of the total antibiotic market. b-Lactam agents form the...

Published: 5/23/2011 | Inventor(s): Marc Devocelle, Stephane Desgranges, Deirdre Fitzgerald Hughes, Timothy Smyth, Carol Ruddle, Hilary Humphreys, Tara Mcfadden

Keywords(s): DeVocelle

Category(s): Antibacterial